S. aureus LPS Overview
B-cell proliferation Class switch recombination Somatic hypermutation M cell Epithelial cell Intestinal immune network for IgA production - Anas platyrhynchos (mallard) - Poly I:C RA MHC class II Isolated lymphoid follicles Peyer's patch Vascular system Inductive site B1 cell Antigen DC CD4+ T-cell Bacteria Antigen Homing DC Recirculation SIgA IgA+ B-cell Gut lumen IgA+plasma cell IgA+plasmablast IgA+ plasmablasts IgA+ B-cell TGFB1 IL4 IL5 IL-2 TCR TNFSF13B TCR CD40LG ICOSLG TNFRSF17 TNFRSF13B CD80 IGH TGFB1 IL10 AICDA CCL25 TNFSF13B pIgR BAFFR CD86 Anpl-DRA Anpl-DRA IL6 MADCAM1 MAP3K14 TNFRSF13B CCR9 IL5 IL6 ITGA4 TNFRSF13B TGFB1 ICOS CD28 APRIL CXCR4 TNFSF13 CCR9 IL5 IL10 IL15RA CCR10 IL-2 IL15 IGH LTBR IL4 AICDA CCL28 IL6 ITGA4 IL10 CXCL12 CD40 IGH Lamina propria gene Class switch recombination Somatic hypermutation Effector site Lamina propria Lamina propria stroma cell Lamina propria stroma cell Terminal B cell differentiation Leukocyte transendothelial migration B cell receptor signaling pathway T cell receptor signaling pathway Antigen processing and presentation B1 cell B2 cell High endothelial venules