S. aureus Poly I:C Overview
cGAMP DNA DNA DNA dsDNA dsDNA Inflammasome dsDNA dsDNA POLR3F M45 IFNB POLR3C POLR3B POLR3H POLR2K IFI202 POLR3E ADAR POLR3G RIG-I E3L RIPK3 CXCL10 DAI IKBKE POLR1C CHUK CASP1 TMEM173 AIM2 MB21D1 IL33 ASC NFKBIA POLR3D NFKB1 RIPK1 CCL4 POLR2F IL6 TBK1 IKBKB MAVS IRF3 POLR2L IFNA POLR2H TREX1 IL18 IL6 IRF7 IL1B CCL5 POLR3A NFKB1 Pyroptosis Oligomerization 5'-ppp dsRNA gene Oligomerization Type I interferons Ubiquitin mediated proteolysis NF-kappa B signaling pathway Proinflammatory cytokines Proinflammatory cytokine processing RIG-I-like receptor signaling pathway Pro-inflammatory cytokines and chemokines Cytosolic DNA-sensing pathway - Anas platyrhynchos (mallard) - LPS