LPS Poly I:C Overview
FOS JUN MAP2K3 MAP2K6 LPS (G-) Chemotactic effects CCL3 CCL5 PIK3R2 MAPK12 IL12B MyD88 IL6 MyD88 PIK3R1 TLR3 PIK3CB TLR6 IRAK4 IRF3 IL8 CCL4 IL1B AKT3 TAB1 IFNAR2 CD14 IFNAR1 TLR9 IKKε IL12A IRAK4 MAP2K1 TOLLIP TRAM MAP2K4 TBK1 IRF7 IRF5 AKT2 LBP RAC1 RIP1 MAPK14 PIK3CD NFKB1 IFNB CXCL9 IKKβ FADD TRAF3 TLR4 NFKB1 IFNB SPP1 MyD88 TRAF6 MAP2K7 MAP2K2 MAP3K8 IKBKG CXCL10 CD80 IFNA CXCL11 CASP8 CHUK TLR2 IRAK1 PIK3CA TICAM1 TLR7 CTSK PIK3R3 STAT1 CD86 TLR5 TIRAP MAPK11 TAK1 TRAF6 MyD88 TIRAP IRAK1 MAPK8 TLR1 CHUK MAPK10 TAB2 LY96 MAPK13 MAPK1 CD40 NFKBIA TLR2 MAPK9 TRAF6 AKT1 TNFA Imidazoquinolin (anti-viral compounds) ssRNA dsRNA Apoptosis Flagellar assembly gene Chemotactic effects Antiviral effects Flagellin Unmethylated CpG DNA T cell stimulation Lipopolysaccharide biosynthesis JAK-STAT signaling pathway MAPK signaling pathway PI3K-Akt signaling pathway Degradation Inflammatory cytokines Costimulatory molecules Cytokine-cytokine receptor interaction Autocrine / Paracrine NF-kappa B signaling pathway Ubiquitin mediated proteolysis MyD88-dependent pathway MyD88-independent pathway Complement and coagulation cascades AP-1 Proinflammatory effects Peptidoglycan (G+) Lipoprotein Lipoarabinomannan (Mycobacteria) Zymosan (Yeast) Inflammatory cytokines p38 JNK Toll-like receptor signaling pathway - Anas platyrhynchos (mallard) - S. aureus TLR2 Endosome