S. aureus Poly I:C Overview
FOS JUN MAP2K3 MAP2K6 LPS (G-) Chemotactic
 effects TICAM1 MAP2K7 NFKBIA PIK3CB TLR4 IFNB RAC1 MyD88 MAP2K1 CTSK STAT1 PIK3R2 IRF7 CCL4 IKBKG MAPK10 LY96 MyD88 MyD88 TOLLIP IL6 CXCL11 TLR3 CCL5 MAPK1 IL12B PIK3R3 LBP PIK3CD TNFA TBK1 IRAK4 CCL3 CD80 MAP3K8 MyD88 IL1B CD86 TRAF6 CXCL10 TLR9 TLR5 RIP1 SPP1 AKT1 NFKB1 CHUK IRAK1 TLR7 TAB1 TLR6 IL12A TRAF3 CASP8 TLR1 MAPK9 TLR2 IFNAR2 MAPK11 TRAM IRF3 TIRAP MAPK8 FADD IKKβ MAPK14 IFNB IRF5 PIK3R1 NFKB1 AKT3 AKT2 IL8 TRAF6 IRAK1 PIK3CA MAP2K2 CD40 CXCL9 IRAK4 TIRAP TRAF6 CD14 IFNAR1 MAPK13 IFNA MAP2K4 TLR2 TAB2 CHUK MAPK12 TAK1 IKKε Imidazoquinolin 
   (anti-viral compounds) 
 ssRNA dsRNA Apoptosis Flagellar assembly gene Chemotactic effects Flagellin Antiviral effects Unmethylated 
CpG DNA T cell stimulation Lipopolysaccharide
biosynthesis JAK-STAT
signaling pathway MAPK signaling
pathway PI3K-Akt signaling
pathway Degradation Costimulatory molecules Inflammatory cytokines Cytokine-cytokine receptor
interaction Autocrine / Paracrine MyD88-dependent
pathway Ubiquitin mediated
proteolysis NF-kappa B signaling
pathway MyD88-independent
pathway Complement and
coagulation cascades AP-1 Proinflammatory effects Peptidoglycan (G+) 
 Lipoprotein 
 Lipoarabinomannan 
 (Mycobacteria) 
 Zymosan (Yeast) Inflammatory cytokines p38 JNK Toll-like receptor signaling pathway - Anas platyrhynchos (mallard) - LPS TLR2 Endosome