S. aureus Poly I:C Overview
Cathelicidin iE-DAP MDP NO IP3 High extracellular Ca2+ DNA Defensins DNA CA2+ DNA ATP 2'-5'olig(A) Hcys K+ DNA dsDNA dsDNA Ca2+ DNA DNA LPS DNA ROS ER T3SS dsRNA Pyroptosis Toxins Bacteria DNA virus T3SS rod DNA virus RNA virus T3SS needle Gram-negative bacteria Cytosolic LPS Phagocytosis Yersinia bacteria Cytosolic bacteria MAPK11 Nemo CCL5 TXNIP Flagellin IL18 GSDMD NFKB1 ASC TMEM173 IFI16 IL18 IL18 ASC TRAF5 TAK1 IL6 GP91 TAB1 MAPK10 HSP90 TNFAIP3 RIPK2 IFNAR1 POP3 NAIP CASP1 IRF7 CARD8 NLRP3 PLCB1 TICAM1 CASP1 Nemo MFN2 TAB3 PANX1 Pyrin ITPR1 VDAC2 XIAP IFI16 NOD1 POP2 RIPK2 MFN1 XIAP ATG16L1 NLRX1 TRPM2 TRAF3 YopJ JUN IL1B VDAC1 IRF7 NOD2 PA TP53BP1 NFKB1 IKBKB IFI16 ANTXR2 MCP-1 SUGT1 GABARAPL2 POP1 JAK1 IFNAR2 BCL2 pro-IL-1β CARD6 RNASEL CASP1 MAVS CASP1 OAS IRAK4 CASP11 ANTXRL CARD9 RHOA IKBKB GBPs ASC ASC DHX33 IRF7 p22phox TYK2 P2RX7 NLRC4 ASC PLCB2 TAB2 NEK7 ASC ATG5 IFNA TNFα IL1B MCU ANTXR1 NFKB1 ERBB2IP VDAC3 NLRP7 CASP1 CASP1 CASP1 NOD2 CASP1 TXN AIM2 IRF9 ERK DRP1 CASP5 NLRP1 IFI16 ITPR2 GABARAPL1 NLRP12 ASC pro-IL-1β TLR4 TRAF2 IL8 MAPK8 GPRC6A CASP4 NAMPT ASC NFKBIA IKBKE MAPK12 MAPK13 IFNA MYD88 IFNA TBK1 CASP1 IL1B NLRP12 TRPM7 IFI16 TRIP6 LUBAC CTSB PA GBPs TRPV2 PRKCD BIRC2 TBK1 MAVS NOD2 CASP11 CASR CASP1 LF IL18 SUGT1 MAPK9 ASC IFNA LF PLCB4 NLRP12 ASC CXCL TRAF6 NLRP6 BCL-XL ITPR3 CHUK TRAF6 Pyrin IL18 STAT1 BRCC3 MAPK14 TXN2 RIPK1 PSTPIP1 TANK NFKBIA ATG12 CARD CASP12 CASP8 pro-CASP1 FADD Pathogenic bacteria Acylated lipopeptides IFN-stimulated genes Stress Epithelial cell damage Bacterial PGN Gram-negative bacteria Pro-inflammatory effects Gram-negative bacteria gene Antimicrobial peptides K+ efflux Mitocondria disfunction Chemokines PAMPs DAMPs ssRNA virus Inflammasomes bacterial toxin Peptidoglycan biosynthesis MAPK signaling pathway Bacterial secretion system Proteasome Damaged lysosome NF-kappa B signaling pathway Pro-inflammatory cytokines Toll-like receptor signaling pathway JNK p38 NOD-like receptor signaling pathway - Anas platyrhynchos (mallard) - LPS Endosome Endosome Mitochondria