S. aureus LPS Overview
DNA cGAMP DNA DNA Inflammasome dsDNA dsDNA dsDNA dsDNA E3L NFKB1 ASC POLR2F IRF3 RIPK1 POLR2L IL33 TREX1 POLR3A POLR3G CASP1 NFKBIA DAI IKBKB POLR3D M45 CHUK CXCL10 RIG-I POLR3F POLR1C POLR2K NFKB1 IL6 POLR3B POLR3E TMEM173 ADAR IL18 POLR2H CCL5 MAVS IRF7 IFNB RIPK3 IFNA CCL4 POLR3H IKBKE IL6 TBK1 POLR3C IL1B MB21D1 IFI202 AIM2 Oligomerization 5'-ppp dsRNA Pyroptosis gene Oligomerization Type I interferons Ubiquitin mediated proteolysis NF-kappa B signaling pathway Proinflammatory cytokines Proinflammatory cytokine processing RIG-I-like receptor signaling pathway Pro-inflammatory cytokines and chemokines Cytosolic DNA-sensing pathway - Anas platyrhynchos (mallard) - Poly I:C